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Dr. Garry Shen MD, PhD

Shen

Correspondance:

Department of Internal Medicine

University of Manitoba

835-715 McDermot Ave

Winnipeg, MB R3E 3P4

Canada

Tel: 204-789-3816

Email: garry.shen@umanitoba.ca

Dr. Garry Shen is a tenure Professor in the Department of Internal Medicine, and Adjunct professor in Departments of Physiology, Food and Human Nutritional Sciences in University of Manitoba. He received his doctorl degrees in Shanghai Jiaotong University and received research training in University of Iowa, Cleveland Clinic Research Institute, University of Alberta and Joslin Diabetes Center in Harvard Medical School. He became a faculty member in University of Manitoba since 1991 and current served as the Associate Director of Diabetes Research Group, Co-Chair of Endocrine Research Group. He has published >140 full sizes paper or books. He has received a numbers of career awards including Alberta Heritage Foundation Postdoctoral Fellowship Award, New Investigator Award from Canadian Lipoprotein Conference and Iacocca Visiting Professor Award from Joslin Diabetes Center, Harvard Medical School. He has been appointed as the Editor-in-Chief of Cardiovascular and Hematological Disorders-Drug Targets Journal since 2007. His research program has been supported by Canadian Institutes of Health Research, Public Health Agency of Canada, Diabetes Canada, the Lawson Foundation, Heart and Stroke Foundation of Canada. He has served as the Principal Investigator and the Chair of Steering Committee of IDEA and Moms in Motion study since 2004.

Selective publications:

Hui A, Philips-Beck W, Campbell R, Sinclair S, Kuzdak C, Courchene E, Roulette M, Mousseau W, Beaulieu D, Wood E, Munroe G, Desjarlais F,  Ludwig S, Wicklow B, McGavock J, Sellers E, Nickel N, Jiang D, Thiessen K, Pylypjuk C, Morris M, Shen Morris M, Shen GX. Impact of Remote Prenatal Education on Program Participation and Breastfeeding in Rural      and   Remote Indigenous Communities EClin Med. (published by the Lancet) 2021;35:100851

Zhao R, Xiang B, Dolinsky V, Xia M, Shen GX. Saskatoon Berry Powder Reduces Hepatic Steatosis and Insulin Resistance in High Fat-High Sucrose Diet-Induced Obese Mice. J Nutr Biochem 2021 95:108778.

Huang F, Zhao R, Xia M, Shen GX. Impact of Cyanidin-3-Glucoside on Gut Microbiota and Relationship with Metabolism and Inflammation in High Fat-High Sucrose Diet-Induced Insulin Resistant Mice. Microorganisms 2020, 8(8), 1238.

Zhao R, Wan P, Shariati-Ievari S Michel A, Shen GX. North American Wild Rice Attenuated Hyperglycemia in High Fat-Induced Obese Mice: Involvement of AMP-Activated Protein Kinase. J Agric Food Chem 2020 Aug 19;68(33):8855-8862.

Guillemette I, Wicklow B, Sellers E; DART A, Shen GX, Dolinsky V, Gordon J, Jassal D, Nickel N, Heather P, McGavock. Exposure to Diabetes and Cardiovascular Disease Risk in Adolescence and Early Adulthood: A Population-Based Birth Cohort Study. Can Med Assoc J 2020;192(39):E1104-E1113

Zhao R, Khafipour E, Sepehri S, Huang F, Beta T, Shen GX. Impact of Saskatoon Berry Powder on Insulin Resistance and Relationship with Intestinal Microbiota in High Fat-High Sucrose Diet-induced Obese Mice. J Nutr Biochem 2019;69:130-138.

Wicklow BA, Sellers EAC, Sharma AK, Kroeker K, Nickel NC, Philips-Beck W, Shen GX. Association of Gestational Diabetes and Type 2 Diabetes Exposure In Utero With the Development of Type 2 Diabetes in First Nations and Non-First Nations Offspring. JAMA Pediatr. 2018;172:724-731

Zhao R, Ghazzawi N, Wu J, Le K, Li C, Moghadasian MH, Siow YL, Apea-Bah FB, Beta,Yin Z, Shen GX. Germinated Brown Rice Attenuates Atherosclerosis and Vascular Inflammation in LDL Receptor-Knockout Mice. J Agri Food Chem. 2018; 66:4512-4520.

The International Weight Management in Pregnancy (i-WIP) Collaborative Group (59 authors). Effect of diet and physical activity based interventions in pregnancy on gestational weight gain and pregnancy outcomes: Individual participant data (IPD) meta-analysis of randomized trials. Br Med J 2017;358:j3119.

Sellers E, Dean HJ, Shafer LA, Martens PJ, Torshizi A, Ludwig S, Phillips-Beck W, Heaman M, Prior HJ, McGavock J, Morris M, Dart AB, Shen GX. Exposure to gestational diabetes: impact on the development of early onset type 2 diabetes in Canadian First Nation and non-First Nation offspring. Diabetes Care 2016;39:2240-2246

Martens PJ, Shafer LA, Dean HJ, Sellers E, Yamamoto J, Ludwig S, Phillips-Beck W, Heaman M, Prior HJ, McGavock J, Morris M, Dart AB, Campbell R, Shen GX. Breastfeeding Initiation Associated with Reduced Incidence of Diabetes in Mothers and Offspring. Obst Gynecol 2016;128:1095-1104.

 

Shen GX, Shafer LA, Martens PJ, Sellers E, Torshizi A, Ludwig S, Phillips-Beck W, Heaman M, Prior HJ, McGavock J, Morris M, Dart AB, Campbell R, Dean HJ. Does First Nations Ancestry Modify the Association between Gestational Diabetes and Subsequent Diabetes: A Historical Prospective Cohort Study Among Women in Manitoba, Canada. Diabet Med. 2016;33:1245-1252.

Reid A, Back L, Hui A, McGavock J, Dean H, Ludwig S,  Sellers E, Shen GX. Reducing barriers for pregnant women in rural or remote First Nations communities to participate in prenatal nutrition and exercise programs. J Fam Med Commun Health 2014;1:1020.

Hui AL, Back L, Ludwig S, Gardiner P, Sevenhuysen G, Dean HJ, Sellers E, McGavock J, Morris M, Jiang D, Shen GX. Effects of lifestyle intervention on dietary intake, physical activity level, and gestational weight gain in pregnant women with different pre-pregnancy Body Mass Index in a randomized control trial. BMC Pregnancy Childbirth. 2014;14:331.

Back L, Hui A, Reid A, Reid A, Sevnehuysen G, Gardiner P, Ludwig S, Shen GX. Comparison of Physical Activity and Nutritional Intake in First Nations Pregnant Women in Remote Communities and Urban-Living Pregnant Women.Can J Diabetes 2012;36:64-67

Hui A, Back L, Ludwig S, Gardiner P, Sevenhuysen G, Dean H, Sellers E, McGavock J, Morris M, Bruce S, Murray R, Shen GX. Lifestyle intervention on diet and exercise reduced excessive gestational weight gain in pregnant women under a randomized controlled trial. Br J Obstetr Gynecol 2012;119:70-77.

Aljohani N, Rempel BM, Ludwig S, Morris M, Cheang M, Murray R, Bruce S, Shen GX.Impact of gestational diabetes on maternal-fetal outcomes: a retrospective cohort study in Manitoba. Clin Invest Med 2008;31:E338-345.

Aljohani N, Rempel BM, Ludwig S, Morris M, McQuillen K, Cheang M, Murray R, Shen GX. Gestational diabetes in Manitoba during a twenty-year period. Clin Invest Med 31:E131-E137.

Hui A, Ludwig S, Gardiner P, Sevenhuysen G, Murray R, Morris M, Shen GX.

Report of a pilot study on community-based exercise and dietary intervention during pregnancy. Can J Diabetes 30:169-175

Zhao R, Shen G.X. Involvement of heat shock factor-1 in glycated low density lipoprotein-induced upregulation of plasminogen activator inhibitor-1 in vascular endothelial cells. Diabetes 2007;56:1436-1444.